This WP (leader: Dr. Rittweger) will assess changes in muscle function, muscle volume, and changes in muscle ultra-structures like mitochondrial function. This WP also includes measuring changes in bone structure before and after the hypoxia bedrest interventions.
1: measure muscle volume, strength and power (see WP1 for muscle strength)
2: quantify muscle ultra-structure and metabolic function (see also WP5 for metabolic function)
3: measure changes in bone mass and geometry
4: assess changes in biochemical markers of bone metabolism